Nitric Oxide and Cellular Maturity Are Key Components of Pro-Inflammatory Cytokine-Induced Apoptosis of Human Fetal Lung Epithelial Cells

Abstract

Inflammation is a major contributor to the pathogenesis of bronchopulmonary dysplasia (BPD). BPD is associated with prematurity of birth, sepsis, with increased production of both cytokines and nitric oxide, and with the shedding of bronchial epithelial cells. The pathological mechanisms involved in this disease remain unclear, in particular the role that… (More)

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@inproceedings{Posencheg2011NitricOA, title={Nitric Oxide and Cellular Maturity Are Key Components of Pro-Inflammatory Cytokine-Induced Apoptosis of Human Fetal Lung Epithelial Cells}, author={Michael A. Posencheg and Andrew J. Gow and Ping Wang and Linda W. Gonzales and Changjiang Guo}, booktitle={The open cell development & biology journal}, year={2011} }