Nitrergic prejunctional inhibition of purinergic neuromuscular transmission in the hamster proximal colon.

@article{Matsuyama2003NitrergicPI,
  title={Nitrergic prejunctional inhibition of purinergic neuromuscular transmission in the hamster proximal colon.},
  author={Hayato Matsuyama and Abubakr M El-Mahmoudy and Yasutake Shimizu and Tadashi Takewaki},
  journal={Journal of neurophysiology},
  year={2003},
  volume={89 5},
  pages={2346-53}
}
Neurogenic ATP and nitric oxide (NO) may play important roles in the physiological control of gastrointestinal motility. However, the interplay between purinergic and nitrergic neurons in mediating the inhibitory neurotransmission remains uncertain. This study investigated whether neurogenic NO modulates the purinergic transmission to circular smooth muscles of the hamster proximal colon. Electrical activity was recorded from circular muscle cells of the hamster proximal colon by using the… CONTINUE READING