Corpus ID: 20383589

Nitrendipine-stimulated release of prostacyclin-like substance in normal and atherosclerotic animals.

@article{Grodziska1987NitrendipinestimulatedRO,
  title={Nitrendipine-stimulated release of prostacyclin-like substance in normal and atherosclerotic animals.},
  author={L. Grodzińska and M. Basista and E. Basista and M. Sławiński and J. Świȩs and J. Stachura and R. Ohlrogge},
  journal={Arzneimittel-Forschung},
  year={1987},
  volume={37 4},
  pages={
          412-5
        }
}
  • L. Grodzińska, M. Basista, +4 authors R. Ohlrogge
  • Published 1987
  • Chemistry, Medicine
  • Arzneimittel-Forschung
  • Nitrendipine (Bayotensin) is a dihydropyridine derivative that appears to preferentially dilate peripheral vessels by a cellular mechanism similar to those found with other calcium blocking agents. In this study nitrendipine when infused (0.2-0.3 mg/kg i.v.) into anaesthetized cats caused a release of a substance disaggregating platelet clumps which had adhered to blood superfused collagen strip. The appearance of this unstable disaggregating substance was prevented by the pretreatment of cats… CONTINUE READING
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