Nitrendipine-stimulated release of prostacyclin-like substance in normal and atherosclerotic animals.
@article{Grodziska1987NitrendipinestimulatedRO, title={Nitrendipine-stimulated release of prostacyclin-like substance in normal and atherosclerotic animals.}, author={L. Grodzińska and M. Basista and E. Basista and M. Sławiński and J. Świȩs and J. Stachura and R. Ohlrogge}, journal={Arzneimittel-Forschung}, year={1987}, volume={37 4}, pages={ 412-5 } }
Nitrendipine (Bayotensin) is a dihydropyridine derivative that appears to preferentially dilate peripheral vessels by a cellular mechanism similar to those found with other calcium blocking agents. In this study nitrendipine when infused (0.2-0.3 mg/kg i.v.) into anaesthetized cats caused a release of a substance disaggregating platelet clumps which had adhered to blood superfused collagen strip. The appearance of this unstable disaggregating substance was prevented by the pretreatment of cats… CONTINUE READING
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