Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension.

  title={Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension.},
  author={Stanislav Kazda and Bernward Garthoff and Andreas M. Knorr},
  journal={Federation proceedings},
  volume={42 2},
Nitrendipine is a calcium antagonistic 1,4-dihydropyridine derivative with a pronounced antihypertensive activity in animal experiment. Similar to other calcium entry blockers, nitrendipine decreases blood pressure by lowering the elevated peripheral vascular resistance. However, its long-term effect differs from that of vasodilators such as hydralazine and minoxidil. In contrast to vasodilators, nitrendipine reduces heart hypertrophy in various forms of experimental hypertension in rats… CONTINUE READING
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