Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality.

@article{Dunlap2008NitratesAN,
  title={Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality.},
  author={Tareisha L Dunlap and Samer O Abdul-Hay and R Esala P Chandrasena and Ghenet K Hagos and Vaishali Sinha and Zhiqiang Wang and Huali Wang and Gregory R J Thatcher},
  journal={Nitric oxide : biology and chemistry},
  year={2008},
  volume={19 2},
  pages={115-24}
}
Properties of the NO-ASA family of NO-donating NSAIDs (NO-NSAIDs), notably NCX 4016 (mNO-ASA) and NCX 4040 (pNO-ASA), reported in more than one hundred publications, have included positive preclinical data in cancer chemoprevention and therapy. Evidence is presented that the antiproliferative, the chemopreventive (antioxidant/electrophile response element… CONTINUE READING