Nitrate biosynthesis in man.

  title={Nitrate biosynthesis in man.},
  author={Linda C Green and K Ruiz de Luzuriaga and David A. Wagner and William Rand and Nawfal W. Istfan and Vernon R. Young and Steven R Tannenbaum},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={78 12},
Nitrate metabolism was investigated in long-term metabolic studies in healthy young men. Under conditions of constant low ingestion of nitrate (less than 180 mumol/day per subject), the amount of nitrate excreted in urine was an average of 4-fold greater than the amount ingested. Balance studies with 15NO3- showed that the source of the excess nitrate in urine was the endogenous biosynthesis of nitrate, rather than the emptying of a body pool. Nitrate biosynthesis occurred when nitrate… CONTINUE READING