Nipple Aspirate Fluid Hormone Concentrations and Breast Cancer Risk

@article{Chatterton2016NippleAF,
  title={Nipple Aspirate Fluid Hormone Concentrations and Breast Cancer Risk},
  author={R. Chatterton and R. Heinz and A. Fought and D. Ivancic and C. Shappell and Subhashini Allu and S. Gapstur and D. Scholtens and P. Gann and Seema A. Khan},
  journal={Hormones and Cancer},
  year={2016},
  volume={7},
  pages={127-136}
}
Prior reports identify higher serum concentrations of estrogens and androgens as risk factors for breast cancer, but steroids in nipple aspirate fluid (NAF) may be more related to risk. Incident breast cancer cases and mammography controls were recruited. Sex steroids were measured in NAF from the unaffected breasts of cases and one breast of controls. Menopausal status and menstrual cycle phase were determined. NAF steroids were purified by HPLC and quantified by immunoassays. Conditional… Expand
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