Nipah virus matrix protein: expert hacker of cellular machines.

  title={Nipah virus matrix protein: expert hacker of cellular machines.},
  author={Ruth E Watkinson and Benhur Lee},
  journal={FEBS letters},
  volume={590 15},
Nipah virus (NiV, Henipavirus) is a highly lethal emergent zoonotic paramyxovirus responsible for repeated human outbreaks of encephalitis in South East Asia. There are no approved vaccines or treatments, thus improved understanding of NiV biology is imperative. NiV matrix protein recruits a plethora of cellular machinery to scaffold and coordinate virion budding. Intriguingly, matrix also hijacks cellular trafficking and ubiquitination pathways to facilitate transient nuclear localization… CONTINUE READING