Nip21 gene expression reduces coxsackievirus B3 replication by promoting apoptotic cell death via a mitochondria-dependent pathway.

Abstract

Our previous studies, using differential mRNA display, suggested that the mouse Nip21 gene may be involved in myocarditis development in the coxsackievirus B3 (CVB3)-infected mouse heart. Sequence comparison indicated that the mouse Nip21 gene shares high sequence homology to human Nip2. This human protein is known to interact with both the apoptosis… (More)

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@article{Zhang2002Nip21GE, title={Nip21 gene expression reduces coxsackievirus B3 replication by promoting apoptotic cell death via a mitochondria-dependent pathway.}, author={Huifang Mary Zhang and Bobby Yanagawa and Paul Kim-Ming Cheung and Honglin Luo and Ji Yuan and D. W. H. Chau and Aikun Wang and Lubos Bohunek and Janet E Wilson and Bruce McManus and Decheng Yang}, journal={Circulation research}, year={2002}, volume={90 12}, pages={1251-8} }