Niosome as a drug carrier for topical delivery of N-acetyl glucosamine

  title={Niosome as a drug carrier for topical delivery of N-acetyl glucosamine},
  author={M. A. Shatalebi and S. Mohammad Mostafavi and Ali Moghaddas},
  booktitle={Research in pharmaceutical sciences},
Niosomes are non-ionic surfactant vesicles that have potential applications in the delivery of hydrophilic and hydrophobic drugs. The topical form of N-acetyl glucosamine (NAG) recently has been considered in the treatment of hyperpigmentation disorders due to its inhibitory effect on thyrosinase enzymes in melanocytes. To improve NAG penetration into the skin we formulated the drug in niosomes and investigated its flux across excised rat skin using Franz diffusion cells. The drug assay was… CONTINUE READING


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