Nilotinib-mediated inhibition of ABCB1 increases intracellular concentration of dasatinib in CML cells: implications for combination TKI therapy

Abstract

H3K36 methylation to Hox-A gene activation and leukaemogenesis. Nat Cell Biol 2007; 9: 804–812. 5 Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H et al. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature 2009; 459: 847–851. 6 Travers AA. Priming the nucleosome: a role for HMGB proteins? EMBO Rep 2003; 4: 131… (More)
DOI: 10.1038/leu.2009.242

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@article{Hiwase2010NilotinibmediatedIO, title={Nilotinib-mediated inhibition of ABCB1 increases intracellular concentration of dasatinib in CML cells: implications for combination TKI therapy}, author={Devendra K Hiwase and Deborah L. White and Stephanie Zrim and V. A. Saunders and J V Melo and Timothy P Hughes}, journal={Leukemia}, year={2010}, volume={24}, pages={658-660} }