Nigrostriatal Modifications After Vanadium Inhalation: An Immunocytochemical and Cytological Approach

  title={Nigrostriatal Modifications After Vanadium Inhalation: An Immunocytochemical and Cytological Approach},
  author={Mar{\'i}a Rosa Avila-Costa and Elisa Flores and Laura Col{\'i}n-Barenque and Juan Luis P{\'e}rez Ord{\'o}{\~n}ez and A. L. Guti{\'e}rrez and Hortencia Geraldine Ni{\~n}o-Cabrera and Patricia Mussali-Galante and Teresa I Fortoul},
  journal={Neurochemical Research},
Vanadium (V) has increased in the air as a component of suspended particles originated from fuel combustion. In this report, a model of inhaled V in mice was implemented to identify the effect that V has in the corpus striatum and substantia nigra, structures with high concentrations of dopamine and scarce antioxidants burden. Mice inhaled 0.02 M V2O5 1 h twice a week and were sacrificed at points from 1 to 8 weeks after inhalation, perfused, and processed for Golgi method and for tyroxine… CONTINUE READING


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