Nigral iron deposition occurs across motor phenotypes of Parkinson's disease.

@article{Jin2012NigralID,
  title={Nigral iron deposition occurs across motor phenotypes of Parkinson's disease.},
  author={Ling Jin and Jian Wang and Hang Jin and Guoqiang Fei and Yuwen Zhang and Weijian Chen and Lei Zhao and Ning Zhao and Xiaoteng Sun and Mengsu Zeng and Chunjiu Zhong},
  journal={European journal of neurology},
  year={2012},
  volume={19 7},
  pages={
          969-76
        }
}
BACKGROUND AND PURPOSE   To investigate whether brain iron deposition correlates with motor phenotypic expressions of Parkinson's disease. METHODS   We subtyped patients with Parkinson's disease according to their main motor symptoms (tremor, rigidity/bradykinesia) into three subgroups: tremor-dominant subgroup, akinetic/rigid-dominant subgroup, or mixed subgroup. The iron levels in bilateral substantia nigra, globus pallidus, putamen, the head of caudate, and red nucleus of 87 patients and… CONTINUE READING
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