Nigella sativa protects against ischaemia/reperfusion injury in rat kidneys.

  title={Nigella sativa protects against ischaemia/reperfusion injury in rat kidneys.},
  author={Omer Bayrak and N{\"u}ket Bavbek and Omer Faruk Karatas and Reyhan Bayrak and Ferhat Çatal and Ersin Çimentepe and Ali Akbaş and Erol Yildirim and Doğan Unal and Ali Akçay},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  volume={23 7},
BACKGROUND Renal ischaemia followed by reperfusion leads to acute renal failure in both native kidneys and renal allografts, which is a complex pathophysiologic process involving hypoxia and free radical (FR) damage. The oil of Nigella sativa (NSO) has been subjected to considerable pharmacological investigations that have revealed its antioxidant activity in different conditions. But there is no previously reported study about its effect on ischaemia/reperfusion (I/R) injury of kidneys. The… CONTINUE READING