Corpus ID: 1984790

Nigella sativa amliorates inflammation and demyelination in the experimental autoimmune encephalomyelitis-induced Wistar rats.

@article{Noor2015NigellaSA,
  title={Nigella sativa amliorates inflammation and demyelination in the experimental autoimmune encephalomyelitis-induced Wistar rats.},
  author={N. A. Noor and H. Fahmy and F. Mohammed and A. Elsayed and N. M. Radwan},
  journal={International journal of clinical and experimental pathology},
  year={2015},
  volume={8 6},
  pages={
          6269-86
        }
}
  • N. A. Noor, H. Fahmy, +2 authors N. M. Radwan
  • Published 2015
  • Medicine
  • International journal of clinical and experimental pathology
  • Multiple sclerosis (MS) is the major, immune-mediated, demyelinating neurodegenerative disease of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a well-established animal model of MS. The aim of the present study was to investigate the protective and ameliorative effects of N. sativa seeds (2.8 g/kg body weight) in EAE-induced Wistar rats. EAE-induced rats were divided into: 1- EAE-induced rats ("EAE" group). 2- "N. sativa + EAE" group received daily oral… CONTINUE READING
    21 Citations
    Cannabis-induced Moto-Cognitive Dysfunction in Wistar Rats: Ameliorative Efficacy of Nigella Sativa.
    • 8
    • PDF
    IN VIVO AND IN VITRO EFFICACY OF NIGELLA SATIVA AQUEOUS EXTRACT ON BLASTOCYSTIS HOMINIS.
    • 1
    • PDF
    Nigella sativa: Valuable perspective in the management of chronic diseases
    • 2
    • Highly Influenced
    Overview of the preclinical pharmacological properties of Nigella sativa (black seeds): a complementary drug with historical and clinical significance.
    • 23
    • PDF
    Compromised axon initial segment integrity in EAE is preceded by microglial reactivity and contact
    • 36

    References

    SHOWING 1-10 OF 112 REFERENCES
    Amelioration of chronic relapsing experimental autoimmune encephalomyelitis (cr-eae) using thymoquinone - biomed 2009.
    • 22
    Improvement of experimental allergic encephalomyelitis (EAE) by thymoquinone; an oxidative stress inhibitor.
    • 69
    The effect of Nigella sativa oil against experimental allergic encephalomyelitis via nitric oxide and other oxidative stress parameters.
    • 22
    Thymoquinone inhibits the activation of NF-kappaB in the brain and spinal cord of experimental autoimmune encephalomyelitis.
    • 59
    Chronologic neuropathology of relapsing experimental allergic encephalomyelitis in the mouse.
    • 163
    Experimental allergic encephalomyelitis: Neutralizing antibody to TGFβ1 enhances the clinical severity of the disease
    • 97
    Protective effects of caffeic acid phenethyl ester against experimental allergic encephalomyelitis-induced oxidative stress in rats.
    • 96
    Chemokine expression in GKO mice (lacking interferon-gamma) with experimental autoimmune encephalomyelitis.
    • 80
    • PDF