Corpus ID: 1984790

Nigella sativa amliorates inflammation and demyelination in the experimental autoimmune encephalomyelitis-induced Wistar rats.

@article{Noor2015NigellaSA,
  title={Nigella sativa amliorates inflammation and demyelination in the experimental autoimmune encephalomyelitis-induced Wistar rats.},
  author={N. A. Noor and H. Fahmy and F. Mohammed and A. Elsayed and N. M. Radwan},
  journal={International journal of clinical and experimental pathology},
  year={2015},
  volume={8 6},
  pages={
          6269-86
        }
}

N. A. Noor, H. Fahmy, +2 authors N. M. Radwan

Published 2015

Medicine

International journal of clinical and experimental pathology

Multiple sclerosis (MS) is the major, immune-mediated, demyelinating neurodegenerative disease of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a well-established animal model of MS. The aim of the present study was to investigate the protective and ameliorative effects of N. sativa seeds (2.8 g/kg body weight) in EAE-induced Wistar rats. EAE-induced rats were divided into: 1- EAE-induced rats ("EAE" group). 2- "N. sativa + EAE" group received daily oral… CONTINUE READING

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