Nicotinic receptor partial agonists modulate alcohol deprivation effect in C57BL/6J mice

@article{Sajja2013NicotinicRP,
  title={Nicotinic receptor partial agonists modulate alcohol deprivation effect in C57BL/6J mice},
  author={Ravi K Sajja and Shafiqur Rahman},
  journal={Pharmacology Biochemistry and Behavior},
  year={2013},
  volume={110},
  pages={161-167}
}
  • Ravi K Sajja, S. Rahman
  • Published 1 September 2013
  • Chemistry, Medicine
  • Pharmacology Biochemistry and Behavior
Relapse is a core feature of alcohol addiction and hinders the pharmacotherapy of alcohol use disorders. Pre-clinical and clinical studies have shown that neuronal nicotinic acetylcholine receptor (nAChR) partial agonists such as cytisine and its derivative, varenicline, reduce alcohol (ethanol) consumption and seeking behavior. However, the effects of these ligands on ethanol relapse are little understood. In the present study, we examined the effects of varenicline and cytisine on alcohol… Expand
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