Nicotinic receptor blockade therapy and smoking cessation.

@article{Clarke1991NicotinicRB,
  title={Nicotinic receptor blockade therapy and smoking cessation.},
  author={Paul B S Clarke},
  journal={British journal of addiction},
  year={1991},
  volume={86 5},
  pages={501-5}
}
Smoking is a behaviour with a significant conditioned component. Attempts to quit will likely fail unless the effects of primary and secondary reinforcers are extinguished. Current smoking cessation methods scarcely address this issue, which may explain why they meet with little success in the long term. In contrast, the administration of centrally-active nicotinic receptor antagonists should provide a means of extinguishing both primary and secondary reinforcers associated with smoking. Thus… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Mechanisms involved in systemic nicotine-induced glutamatergic synaptic plasticity on dopamine neurons in the ventral tegmental area.

Ming Gao, Yu Jin, +3 authors Jie Wu
The Journal of neuroscience : the official journal of the Society for Neuroscience • 2010
View 2 Excerpts

Similar Papers

Loading similar papers…