Nicotinic plant poisoning

  title={Nicotinic plant poisoning},
  author={Leo J. Schep and Robin J Slaughter and D Michael G Beasley},
  journal={Clinical Toxicology},
  pages={771 - 781}
Introduction. A wide range of plants contain nicotinic and nicotinic-like alkaloids. Of this diverse group, those that have been reported to cause human poisoning appear to have similar mechanisms of toxicity and presenting patients therefore have comparable toxidromes. This review describes the taxonomy and principal alkaloids of plants that contain nicotinic and nicotinic-like alkaloids, with particular focus on those that are toxic to humans. The toxicokinetics and mechanisms of toxicity of… 

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A number of derivatives and analogues ofimidacloprid have been generated to date, one of which has a characteristic tetrahydro-3-furylmethyl group instead of the pyridine-like rings of others neonicotinoids.

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A case of respiratory arrest due to nicotinic alkaloid poisoning from the ingestion of Nicotiana glauca is presented, describing how modern technology and thorough history taking can combine to provide the best possible patient care.



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Another death due to ingestion of Nicotiana glauca.

The case of a 43-year-old man found dead after apparently drinking a water extract of Nicotiana glauca further supports the view that, in the human, anabasine is considerably more toxic than nicotine.

Gas chromatographic determination of toxic quinolizidine alkaloids in blue cohosh Caulophyllum thalictroides (L.) Michx

Blue cohosh (Caulophyllum thalictroides (L.) Michx., Berberidaceae) is a North American perennial herb which is found as an ingredient in dietary supplement products in the United States. The plant

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A GC/MS method was used for the identification of anabasine as the main constituent in the leaves, food extract, blood, and the urine of the deceased and to establish its presence.

A fatal poisoning from Nicotiana glauca.

Anabasine, the major, highly toxic alkaloid of the shrub, Nicotiana glauca (tree tobacco) was subsequently identified in all body specimens examined using gas chromatography/mass spectrometry.

Determination of saponins and alkaloids in Caulophyllum thalictroides (blue cohosh) by high-performance liquid chromatography and evaporative light scattering detection.

An HPLC method has been developed which permits the determination of the triterpene saponins in the plant and also the separation of four alkaloids, and remarkable qualitative and quantitative variations were revealed.