Nicotinic depolarization activates calcium dependent gK in myenteric neurons.

@article{Tokimasa1983NicotinicDA,
  title={Nicotinic depolarization activates calcium dependent gK in myenteric neurons.},
  author={Takayuki Tokimasa and Emilio Cherubini and R Alan North},
  journal={Brain research},
  year={1983},
  volume={263 1},
  pages={57-62}
}
Intracellular recordings were made from S type neurons in the myenteric plexus of the guinea-pig ileum. Acetylcholine (ACh) was applied directly onto the soma membrane by iontophoresis with visual placement of the iontophoretic pipette. Fast nicotinic depolarizations were evoked which were followed by slow muscarinic depolarizations. After application of hyoscine to block the slow muscarinic depolarization, the nicotinic depolarization was found to be followed by a hyperpolarization. This… CONTINUE READING