Nicotinic acid-adenine dinucleotide phosphate activates the skeletal muscle ryanodine receptor.

  title={Nicotinic acid-adenine dinucleotide phosphate activates the skeletal muscle ryanodine receptor.},
  author={Martin Hohenegger and Josef Suko and Regina Gscheidlinger and Helmut Drobny and Andreas Zidar},
  journal={The Biochemical journal},
  volume={367 Pt 2},
Calcium is a universal second messenger. The temporal and spatial information that is encoded in Ca(2+)-transients drives processes as diverse as neurotransmitter secretion, axonal outgrowth, immune responses and muscle contraction. Ca(2+)-release from intracellular Ca(2+) stores can be triggered by diffusible second messengers like Ins P (3), cyclic ADP-ribose or nicotinic acid-adenine dinucleotide phosphate (NAADP). A target has not yet been identified for the latter messenger. In the present… CONTINUE READING


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