Nicotinic acid/niacinamide and the skin

@article{Gehring2004NicotinicAA,
  title={Nicotinic acid/niacinamide and the skin},
  author={Wolfgang Gehring},
  journal={Journal of Cosmetic Dermatology},
  year={2004},
  volume={3}
}
  • W. Gehring
  • Published 1 April 2004
  • Chemistry, Medicine
  • Journal of Cosmetic Dermatology
Nicotinic acid (also generally known as niacin) and niacinamide (also known as nicotinamide) are similarly effective as a vitamin because they can be converted into each other within the organism. The blanket term vitamin B3 is used for both. 
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    Journal of cosmetic dermatology
  • 2014
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The possible side effects and consequences of excessive Nicotinamide exposure are reviewed, including suggestions nicotinamide might have a role in the development of diabetes, Parkinson's disease, and liver damage.
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This study investigates whether the induction of flushing by nicotinic acid and nonivamide causes an inflammatory response that influences the composition of immune cells present in a capillary blood sample.
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Azelaic acid modulates the inflammatory response in normal human keratinocytes through PParγ activation through PPARγ activation.
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The plant based foods such as cereals and legumes, with a ratio of 87% nicotinic acid presence, standout as the best source ofNicotinic Acid deficiency in human and encouraging regular intake of those cereal and legume samples containing rich nicotini acid would remove nicotinIC acid deficiency inhuman.
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  • M. Namazi
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It is speculated that MIF inhibition may be responsible for the steroid-sparing effect of nicotinamide, as MIF, in contrast with other cytokines, is upregulated by steroids and overrides the anti-inflammatory effects of these agents.
Water‐in‐oil microemulsions composed of monoolein enhanced the transdermal delivery of nicotinamide
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The oil‐based formulations of Nicotinamide are expected to enhance the transdermal delivery efficiency of nicotinamide.
The protective effect of niacinamide on CHO AA8 cell line against ultraviolet radiation in the context of main cytoskeletal proteins.
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The results confirmed the harmful effects of UV radiation on CHO AA8 cell line and showed that niacinamide can protect cells against these factors, and the mechanism of action may be related to the stabilization of the cell cytoskeleton.
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TLDR
Nicotinamide gel provides potent antiinflammatory activity without the risk of inducing bacterial resistance.
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TLDR
A patient with tuberculous meningitis developed a pellagra-like skin eruption after treatment with isoniazid and a topical preparation of niacinamide (nico-tinamide) was applied, and there was noticeable improvement in the patient's depression and apathy.
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
It is suggested that two phases of inflammation may occur: an early phase sensitive to antihistamines and non‐steroidal antiinflammatory drugs and a late phase of extensive cell damage that was not sensitive to these drug pretreatments.
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TLDR
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TLDR
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