Nicotine psychobiology: how chronic-dose prospective studies can illuminate some of the theoretical issues from acute-dose research

@article{Parrott2005NicotinePH,
  title={Nicotine psychobiology: how chronic-dose prospective studies can illuminate some of the theoretical issues from acute-dose research},
  author={Andrew C. Parrott},
  journal={Psychopharmacology},
  year={2005},
  volume={184},
  pages={567-576}
}
  • A. Parrott
  • Published 7 February 2006
  • Psychology, Biology
  • Psychopharmacology
RationaleTo illustrate how prospective cigarette smoking research can illuminate some of the theoretical dilemmas about nicotine psychobiology from acute dose research.Methods and resultsWhen briefly deprived smokers are administered nicotine, they display a range of psychobiological ‘gains’, with improved cognitive performance, feelings of contentment, and reduced feelings of stress or depression. However, abstinence leads to decrements in all these functions. The balance between the deficits… 
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The main objective of this study was to investigate the causal relationship between smoking and depression/ anxiety, and specially the direction of this relationship, in order to analyze the link
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References

SHOWING 1-10 OF 117 REFERENCES
Cigarette-Derived Nicotine is not a Medicine
  • A. Parrott
  • Psychology
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
  • 2003
TLDR
There is no empirical evidence that cigarettes provide medicinal benefits, but extensive data showing that nicotine dependency heightens psychological distress in tobacco smokers is shown.
Smoking cessation leads to reduced stress, but why?
  • A. Parrott
  • Psychology
    The International journal of the addictions
  • 1995
TLDR
The deprivation reversal model (Schachter), suggests that smoking reverses the deleterious effects of deprivation; cessation will then lead to a period of increased stress, followed by a return to baseline, consistent with a third explanation, namely that smoking causes stress.
Recommendation for the assessment of tobacco craving and withdrawal in smoking cessation trials.
  • S. Shiffman, R. West, D. Gilbert
  • Psychology
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
  • 2004
TLDR
Assessment of nicotine withdrawal and craving in clinical trials of smoking cessation therapies is addressed; different designs and approaches are needed to investigate the process and natural history of craving and withdrawal.
Lack of efficacy of a nicotine transdermal treatment on motor and cognitive deficits in Parkinson's disease
Nesbitt's Paradox resolved? Stress and arousal modulation during cigarette smoking.
TLDR
This review confirms that cigarette smoking generates physiological and psychological changes which are normally incompatible, namely increased arousal together with decreased stress, but shows that they are dependent upon various factors, particularly the degree of nicotine deprivation.
Effects of nicotine dependence on diurnal variations of subjective activation and mood.
TLDR
Differences exist in the circadian rhythmicity between non-smokers and smokers, and that the level of nicotine dependence in smokers is a relevant factor for the interpretation of the diurnal variations, are confirmed.
Cigarette Smoking and Abstinence: Comparative Effects Upon Cognitive Task Performance and Mood State over 24 Hours
Twenty regular smokers were assessed over 24‐h of normal cigarette smoking, and an equivalent period of abstinence. In both conditions, a non‐deprived baseline was followed by performance tests 2, 6
Effects of cigarette smoking on spatial working memory and attentional deficits in schizophrenia: involvement of nicotinic receptor mechanisms.
TLDR
Cigarette smoking may selectively enhance Visuospatial working memory (VSWM) and attentional deficits in smokers with schizophrenia, which may depend on nAChR stimulation.
Non-nicotine pharmacotherapies for nicotine dependence.
TLDR
In patients with schizophrenia, a combination of behavioral therapy and pharmacotherapy currently offers the best option, and a primary FDA approved non-nicotine pharmacotherapy agent is bupropion (Zyban).
Comparative mood states and cognitive skills of cigarette smokers, deprived smokers and nonsmokers
Regular cigarette smokers (n=15), overnight deprived smokers (n=15) and nonsmokers (n=20), were assessed on a battery of mood questionnaires and cognitive performance tasks, before and after a
...
1
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3
4
5
...