Nicotine promotes contribution of bone marrow-derived cells to experimental choroidal neovascularization in mice.

@article{Hou2008NicotinePC,
  title={Nicotine promotes contribution of bone marrow-derived cells to experimental choroidal neovascularization in mice.},
  author={Hui-yuan Hou and Yu-sheng Wang and Jian-Feng Xu and Bai-ren Wang},
  journal={Experimental eye research},
  year={2008},
  volume={86 6},
  pages={983-90}
}
Nicotine can increase size and severity of experimental choroidal neovascularization (CNV); however, the mechanism is uncertain. Recent studies demonstrated that the development of CNV involves the contribution of bone marrow-derived cells (BMCs). This study aims to investigate the effects and the potential mechanism of nicotine on BMCs' contribution to CNV. Green fluorescent protein (GFP) chimeric mice were developed by transplanting bone marrow cells from GFP transgenic mice to C57BL/6J mice… CONTINUE READING
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Cigarette smoke increases severity of experimental choroidal neovascularization (CNV): role of inflammation

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