Nicotine prevents the apoptosis induced by menadione in human lung cancer cells.

@article{Zhang2006NicotinePT,
  title={Nicotine prevents the apoptosis induced by menadione in human lung cancer cells.},
  author={Tao Zhang and Heng Lu and Xuan Shang and Yihao Tian and Congyi Zheng and Shiwen Wang and Hanhua Cheng and Rongjia Zhou},
  journal={Biochemical and biophysical research communications},
  year={2006},
  volume={342 3},
  pages={
          928-34
        }
}
Approximately 50% of long-term cigarette smokers die prematurely from the adverse effects of smoking, including on lung cancer and other illnesses. Nicotine is a main component in tobacco and has been implicated as a potential factor in the pathogenesis of human lung cancer. However, the mechanism of nicotine action in the development of lung cancer remains largely unknown. In the present study, we designed a nicotine-apoptosis system, by pre-treatment of nicotine making lung cancer cell A549… CONTINUE READING
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