Nicotine-induced plasma corticosterone is attenuated by social interactions in male and female adolescent rats.

@article{Pentkowski2011NicotineinducedPC,
  title={Nicotine-induced plasma corticosterone is attenuated by social interactions in male and female adolescent rats.},
  author={Nathan S. Pentkowski and Michael R Painter and Kenneth J. Thiel and Natalie A. Peartree and Timothy H.C. Cheung and Pierre Deviche and M Adams and Jes{\'u}s Alba and Janet L. Neisewander},
  journal={Pharmacology, biochemistry, and behavior},
  year={2011},
  volume={100 1},
  pages={1-7}
}
Most smokers begin smoking during adolescence, a period during which social reward is highly influential. Initial exposure to nicotine can produce anxiogenic effects that may be influenced by social context. This study examined play behavior and plasma corticosterone following nicotine administration (0.6 mg/kg, s.c.) in both male and female adolescent (PND39) Sprague-Dawley rats in either isolate or social contexts. In blood samples collected immediately following the 15-min test session… CONTINUE READING

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