Nicotine induced locomotor activity in rats: the role of Pavlovian conditioning.

@article{Hakan1988NicotineIL,
  title={Nicotine induced locomotor activity in rats: the role of Pavlovian conditioning.},
  author={Robert L. Hakan and Charles J. Ksir},
  journal={Pharmacology, biochemistry, and behavior},
  year={1988},
  volume={29 4},
  pages={661-5}
}
Rats repeatedly exposed to small doses of nicotine will demonstrate a significant augmentation of locomotor activity in response to a subsequent test dose of nicotine. A sensitization of brain tissue is hypothesized to account for this effect but Pavlovian conditioning might also be a major factor. Therefore the present study assessed the possible role of… CONTINUE READING