Nicotine induced locomotor activity in rats: The role of Pavlovian conditioning

@article{Hakan1988NicotineIL,
  title={Nicotine induced locomotor activity in rats: The role of Pavlovian conditioning},
  author={Robert L. Hakan and Charles J. Ksir},
  journal={Pharmacology Biochemistry and Behavior},
  year={1988},
  volume={29},
  pages={661-665}
}
Rats repeatedly exposed to small doses of nicotine will demonstrate a significant augmentation of locomotor activity in response to a subsequent test dose of nicotine. A sensitization of brain tissue is hypothesized to account for this effect but Pavlovian conditioning might also be a major factor. Therefore the present study assessed the possible role of Pavlovian conditioning in this nicotine effect. Two experiments were conducted. In the first, subjects were administered either saline or… CONTINUE READING

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