Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancer.

@article{Minna2003NicotineEA,
  title={Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancer.},
  author={John D. Minna},
  journal={The Journal of clinical investigation},
  year={2003},
  volume={111 1},
  pages={31-3}
}
  • John D. Minna
  • Published 2003 in The Journal of clinical investigation
Forty-eight million Americans smoke because of addiction to nicotine, and prevention of smoking initiation and new methods for aiding in smoking cessation are some of the most important opportunities for disease prevention available (1). This smoking addiction results from nicotine acting on neuronal nicotinic acetylcholine receptors (nAchRs) in the brain in key regions controlling behavior. There is detailed structural and functional information on neuronal nAchRs that are the prototype of… CONTINUE READING