Nicotine-evoked transmitter release from synaptosomes: functional association of specific presynaptic acetylcholine receptors and voltage-gated calcium channels.

@article{Kulak2001NicotineevokedTR,
  title={Nicotine-evoked transmitter release from synaptosomes: functional association of specific presynaptic acetylcholine receptors and voltage-gated calcium channels.},
  author={Jennifer M. Kulak and John McIntosh and Doju Yoshikami and Baldomero M Olivera},
  journal={Journal of neurochemistry},
  year={2001},
  volume={77 6},
  pages={1581-9}
}
It has previously been shown that nicotine-evoked dopamine release from rat striatal synaptosomes and nicotine-evoked norepinephrine release from hippocampal synaptosomes are mediated by distinct nicotinic acetylcholine receptor (nAChR) subtypes. In the present study, the functional association of these nicotinic receptors with specific subtypes of voltage-gated calcium channels was examined. Cd(2+) (200 microM), as well as omega-conotoxin MVIIC (5 microM), blocks approximately 85% of nicotine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2013
View 12 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…