Nicotine enhances Morris water maze performance of young and aged rats.

@article{Socci1995NicotineEM,
  title={Nicotine enhances Morris water maze performance of young and aged rats.},
  author={Daniela Socci and Paul R. Sanberg and Gary W. Arendash},
  journal={Neurobiology of aging},
  year={1995},
  volume={16 5},
  pages={857-60}
}
We have recently demonstrated that nicotine administration improves the acquisition and/or memory retention of aged rats in 17-arm radial maze, Lashley III maze, and one-way active avoidance testing. The present study extends our evaluation of nicotine's cognition-enhancing potential by determining the effect of nicotine on acquisition and retention of the Morris water maze in young adult (2 to 3 months old) and aged (25 to 26 months old) Sprague-Dawley rats. For 3 days prior to the onset of… CONTINUE READING

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