Nicotine decreases blood alcohol concentrations in adult rats: a phenomenon potentially related to gastric function.

@article{Parnell2006NicotineDB,
  title={Nicotine decreases blood alcohol concentrations in adult rats: a phenomenon potentially related to gastric function.},
  author={Scott E Parnell and James R. West and Wushun Chen},
  journal={Alcoholism, clinical and experimental research},
  year={2006},
  volume={30 8},
  pages={
          1408-13
        }
}
BACKGROUND In spite of the fact that drinking and smoking often occur together, little is known about the pharmacokinetic interaction between alcohol and nicotine. Previous research in neonatal rats demonstrated that nicotine reduces blood alcohol concentrations (BACs) if alcohol and nicotine are administered simultaneously. However, it is unclear whether such a phenomenon can be observed in adult subjects, given the fact that there is an ontogenetic difference in alcohol metabolism. METHODS… CONTINUE READING
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