Nicotine and methamphetamine share discriminative stimulus effects.

  title={Nicotine and methamphetamine share discriminative stimulus effects.},
  author={Michael B Gatch and Elva Flores and Michael J. Forster},
  journal={Drug and alcohol dependence},
  volume={93 1-2},
BACKGROUND Nicotine and methamphetamine are both abused in similar settings, sometimes together. Because there are known interactions between central nicotinic acetylcholine receptors and dopamine receptors, it is of interest to characterize the nature of the interaction of these two compounds in vivo. METHODS The purpose of this study was to characterize the extent to which these two compounds produce similar discriminative stimulus effects and to identify pharmacological mechanisms for… CONTINUE READING


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