Nicotine Stimulates Nerve Growth Factor in Lung Fibroblasts through an NFκB-Dependent Mechanism

@inproceedings{Wongtrakool2014NicotineSN,
  title={Nicotine Stimulates Nerve Growth Factor in Lung Fibroblasts through an NFκB-Dependent Mechanism},
  author={Cherry Wongtrakool and Kora Grooms and Kaiser M. Bijli and Kristina Crothers and Anne R. Fitzpatrick and Craig M Hart and Marco Idzko},
  booktitle={PloS one},
  year={2014}
}
RATIONALE Airway hyperresponsiveness (AHR) is classically found in asthma, and persistent AHR is associated with poor asthma control. Although airway smooth muscle (ASM) cells play a critical pathophysiologic role in AHR, the paracrine contributions of surrounding cells such as fibroblasts to the contractile phenotype of ASM cells have not been examined… CONTINUE READING