Nicotine, brain nicotinic receptors, and neuropsychiatric disorders.

  title={Nicotine, brain nicotinic receptors, and neuropsychiatric disorders.},
  author={Stefan Mihailescu and Ren{\'e} Drucker-Col{\'i}n},
  journal={Archives of medical research},
  volume={31 2},
Neuronal nicotinic acetylcholine receptors (nAChRs) represent a large family of ligand-gated cation channels with diverse structures and properties. In contrast to the muscular nAChRs, the physiological functions of neuronal nAChRs are not well defined to date. Behavioral studies indicate that brain nAChRs participate in complex functions such as attention, memory, and cognition, whereas clinical data suggest their involvement in the pathogenesis of certain neuropsychiatric disorders (Alzheimer… CONTINUE READING


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