Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes.

Abstract

Circulating NAMPT (PBEF/visfatin) has pleiotropic functions and is secreted from adipocytes. Since it is doubtful whether serum levels can be explained by secretion from adipocytes alone, we asked whether hepatocytes are also able to liberate NAMPT. Using HepG2 cells and primary rat and human hepatocytes, release of NAMPT into the cell culture supernatant… (More)
DOI: 10.1016/j.bbrc.2009.11.066

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@article{Garten2010NicotinamideP, title={Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes.}, author={A Garten and Susanne Petzold and Anja Barnikol-Oettler and Antje K{\"o}rner and Wolfgang E. Thasler and J{\"u}rgen Kratzsch and Wendy Kiess and Rodolfo Gebhardt}, journal={Biochemical and biophysical research communications}, year={2010}, volume={391 1}, pages={376-81} }