Nicotinamide inhibits nuclear factor-kappa B translocation after transient focal cerebral ischemia

@article{Chen2012NicotinamideIN,
  title={Nicotinamide inhibits nuclear factor-kappa B translocation after transient focal cerebral ischemia},
  author={Tsung-ying Chen and Miao-Hui Lin and Wei-Ting Lee and Sheng-Yang Huang and Ying-Hsin Chen and Ai-Chiang Lee and Hsiao-Wen Lin and E. Lee},
  journal={Critical Care Medicine},
  year={2012},
  volume={40},
  pages={532–537}
}
Objective: We explored the putative anti-inflammatory effects of nicotinamide against experimental stroke. Design: Prospective laboratory study. Setting: Research laboratory in a university teaching hospital. Subjects: Adult male Sprague-Dawley rats (250–300 g). Interventions: The antioxidant, radical scavenging, and anti-inflammatory actions of nicotinamide were evaluated using a panel of acellular assays and lipopolysaccharide-stimulated RAW 264.7 and BV2 cells. Animals were subjected to… Expand
Biphasic Activation of Nuclear Factor-Kappa B in Experimental Models of Subarachnoid Hemorrhage In Vivo and In Vitro
Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress
Fusaric acid induces NRF2 as a cytoprotective response to prevent NLRP3 activation in the liver derived HepG2 cell line.
...
1
2
...

References

SHOWING 1-10 OF 18 REFERENCES
Nicotinamide therapy protects against both necrosis and apoptosis in a stroke model
Inhibition of Poly(ADP-Ribose) Polymerase Suppresses Inflammation and Promotes Recovery after Ischemic Injury
Nicotinamide is a potent inhibitor of proinflammatory cytokines
Prevention of Nitric Oxide-Induced Neuronal Injury Through the Modulation of Independent Pathways of Programmed Cell Death
The effects of nicotinamide on energy metabolism following transient focal cerebral ischemia in Wistar rats
...
1
2
...