Nicotinamide N-methyltransferase protein expression in renal cell cancer

@article{Zhang2009NicotinamideNP,
  title={Nicotinamide N-methyltransferase protein expression in renal cell cancer},
  author={Jun Yu Zhang and Xin-you Xie and Su-wen Yang and Jin Wang and Chao He},
  journal={Journal of Zhejiang University SCIENCE B},
  year={2009},
  volume={11},
  pages={136-143}
}
To understand the function of nicotinamide N-methyltransferase (NNMT) protein as tumor biomarker in renal carcinoma. Recombinant NNMT protein was used to prepare monoclonal antibodies by hybridoma technique. The diagnostic and prognostic function of NNMT protein in renal carcinoma was evaluated by analyzing 74 renal cancer tissues through immunohistochemical staining for NNMT by using the prepared antibodies. Two hybridomas named 2F8 and 1E7 stably secreting the monoclonal antibodies were… CONTINUE READING

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