Nicotinamide N-methyltransferase protein expression in renal cell cancer

  title={Nicotinamide N-methyltransferase protein expression in renal cell cancer},
  author={Jun Yu Zhang and Xin-you Xie and Su-wen Yang and Jin Wang and Chao He},
  journal={Journal of Zhejiang University SCIENCE B},
To understand the function of nicotinamide N-methyltransferase (NNMT) protein as tumor biomarker in renal carcinoma. Recombinant NNMT protein was used to prepare monoclonal antibodies by hybridoma technique. The diagnostic and prognostic function of NNMT protein in renal carcinoma was evaluated by analyzing 74 renal cancer tissues through immunohistochemical staining for NNMT by using the prepared antibodies. Two hybridomas named 2F8 and 1E7 stably secreting the monoclonal antibodies were… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 27 references

Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells.

The Journal of clinical endocrinology and metabolism • 2003
View 8 Excerpts
Highly Influenced

Are poly(ADP-ribosyl)ation by PARP-1 and deacetylation by Sir2 linked?

BioEssays : news and reviews in molecular, cellular and developmental biology • 2003
View 3 Excerpts
Highly Influenced

Expression of erythropoietin and its receptor in human renal cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine • 2009
View 2 Excerpts

Serum levels of nicotinamide

H. Akiyama

Production and characterization of monoclonal antibodies to nucleoprotein of Marburg virus

J. B. Zhang, X. M. Lu, +5 authors Z. N. Yu
Hybridoma • 2008
View 1 Excerpt

Similar Papers

Loading similar papers…