Nicotinamide N-methyltransferase overexpression is associated with Akt phosphorylation and indicates worse prognosis in patients with nasopharyngeal carcinoma

@article{Win2013NicotinamideNO,
  title={Nicotinamide N-methyltransferase overexpression is associated with Akt phosphorylation and indicates worse prognosis in patients with nasopharyngeal carcinoma},
  author={Khin Than Win and Sung-Wei Lee and H. Lisa Huang and Li-Ching Lin and Ching-Yih Lin and Chung-Hsi Hsing and L. T. Tai-Hua Chen and C. Li},
  journal={Tumor Biology},
  year={2013},
  volume={34},
  pages={3923-3931}
}
Nicotinamide N-methyltransferase (NNMT) is overexpressed in many human cancers and is associated with poor prognosis. Akt (also known as protein kinase B) is an evolutionarily conserved serine/threonine kinase, serving as a downstream effector of the phosphatidylinositol 3-kinase signaling pathway. NNMT was first identified as a differentially upregulated gene in nasopharyngeal cancer tissues through data mining from published transcriptomic databases. Since no prior study has attempted to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 40 references

Similar Papers

Loading similar papers…