Nickel transport systems in microorganisms

  title={Nickel transport systems in microorganisms},
  author={Thomas Eitinger and Marie-Andr{\'e}e Mandrand-Berthelot},
  journal={Archives of Microbiology},
The transition metal Ni is an essential cofactor for a number of enzymatic reactions in both prokaryotes and eukaryotes. Molecular analyses have revealed the existence of two major types of high-affinity Ni2+ transporters in bacteria. The Nik system of Escherichia coli is a member of the ABC transporter family and provides Ni2+ ion for the anaerobic biosynthesis of hydrogenases. The periplasmic binding protein of the transporter, NikA, is likely to play a dual role. It acts as the primary… CONTINUE READING


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Purification and characterization of the periplasmic nickel binding protein NikA of Escherichia coli K - 12

K DePina, V Desjardin, Mandrand-Berthelot M-A, G Giordano, Wu L-F
Eur J Biochem • 1999

An X - ray absorption spectroscopic structural investigation of the nickel site in Escherichia coli NikA protein

CB Allan, Wu L-F, +5 authors MJ Maroney
Inorg Chem • 1998

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