Nickel deficiency gives rise to the defective hydrogenase phenotype of hydC and fnr mutants in Escherichia coli.

@article{Wu1989NickelDG,
  title={Nickel deficiency gives rise to the defective hydrogenase phenotype of hydC and fnr mutants in Escherichia coli.},
  author={Long Fei Wu and Marie-Andr{\'e}e Mandrand-Berthelot and Robbie Waugh and Caroline J. Edmonds and Sean Holt and David H. Boxer},
  journal={Molecular microbiology},
  year={1989},
  volume={3 12},
  pages={1709-18}
}
Hydrogenase activity and other hydrogenase-related functions can be restored to hydC mutants by the specific addition of nickel salts to the growth medium. These mutants are defective in all three hydrogenase isoenzymes and the restoration is dependent upon protein synthesis. The cellular nickel content of the mutant when grown in LB medium is less than 1% of that of the parental strain. Partial suppression of the hydrogenase phenotype of hydC mutants occurs when growth takes place in a… CONTINUE READING

From This Paper

Topics from this paper.
32 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

Similar Papers

Loading similar papers…