Nickel-Iron Hydrogenases: High-Resolution Crystallography Resolves the Hydride, but Not the Debate.

  • David Schilter
  • Published 2015 in
    Chembiochem : a European journal of chemical…

Abstract

An (X-ray) eye for detail: Modern high-resolution protein crystallography allows H atoms to be located. Applied to nickel-iron hydrogenase, X-ray structural analysis has finally confirmed the presence of an active-site hydride and thiol, as well as unveiling the intricate pathways that protons take to and from the active site.

DOI: 10.1002/cbic.201500270

Cite this paper

@article{Schilter2015NickelIronHH, title={Nickel-Iron Hydrogenases: High-Resolution Crystallography Resolves the Hydride, but Not the Debate.}, author={David Schilter}, journal={Chembiochem : a European journal of chemical biology}, year={2015}, volume={16 12}, pages={1712-4} }