Nickel Allergy and Our Children's Health: A Review of Indexed Cases and a View of Future Prevention

@article{Jacob2015NickelAA,
  title={Nickel Allergy and Our Children's Health: A Review of Indexed Cases and a View of Future Prevention},
  author={Sharon E Jacob and Alina Goldenberg and Janice L. Pelletier and L Fonacier and Richard P. Usatine and Nanette B Silverberg},
  journal={Pediatric Dermatology},
  year={2015},
  volume={32}
}
Nickel is the leading cause of allergic contact dermatitis (ACD) from early childhood through adolescence. Studies have shown that skin piercings and other nickel‐laden exposures can trigger the onset of nickel ACD in those who are susceptible. Nickel ACD causes a vast amount of cutaneous disease in children. Cases of nickel ACD in children have been reported in peer‐reviewed literature from 28 states. Common items that contain inciting nickel include jewelry, coins, zippers, belts, tools, toys… Expand
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TLDR
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TLDR
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The “Jewelry Addict”: Allergic Contact Dermatitis from Repetitive Multiple Children's Jewelry Exposures
TLDR
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References

SHOWING 1-10 OF 94 REFERENCES
Nickel and Cobalt Release From Children’s Toys Purchased in Denmark and the United States
TLDR
Toys are a commonly overlooked source of nickel exposure and sensitization, and the parents of children with positive nickel patch test reactions should be told that toys may release nickel and be a potential chemical source in the manifestation of allergic contact dermatitis. Expand
Nickel Contact Hypersensitivity in Children
TLDR
It is posited that the presence of a positive family history may be a positive predictor of nickel allergic contact dermatitis, requiring nickel avoidance, especially in atopic children. Expand
Nickel hypersensitivity in the orthodontic patient.
  • J. Bass, H. Fine, G. Cisneros
  • Medicine
  • American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
  • 1993
TLDR
There may be a risk of sensitizing patients to nickel with long-term exposure to nickel-containing appliances as occurs in routine orthodontic therapy. Expand
Characteristics of nickel-allergic dermatitis patients seen in private dermatology clinics in Denmark: a questionnaire study.
TLDR
It is concluded that nickel allergy has decreased among young females with dermatitis due to the nickel regulation in Denmark. Expand
Nickel coinage in the United States: the history of a common contact allergen.
TLDR
The history of nickel as a 3- and 5-cent piece and as the base metal used in most of the coins currently in circulation are discussed. Expand
Allergic Contact Dermatitis in Children: Review of the Past Decade
TLDR
The relationship between ACD and atopic dermatitis (AD) is complicated with conflicting reports of prevalence in the literature; however, in a patient with dermatitis not responding to traditional therapies, or with new areas of involvement, ACD should be considered as part of the work-up. Expand
Nickel allergy and hand dermatitis in a stratified sample of the Danish female population: an epidemiological study including a statistic appendix.
TLDR
In future efforts to reduce direct skin contact with nickel, the close relation between nickel allergy and hand eczema should be the main argument and statistical methods based on the incidence density will be useful in the evaluation of efforts. Expand
Nickel contact dermatitis in children.
Nickel is the most commonly detected cutaneous allergen on patch testing in the United States for children. The ubiquitous nature of nickel as a hardening agent in metal products makes avoidanceExpand
Adverse reactions to orthodontic appliances in nickel-allergic patients.
TLDR
The relationship between NA and ODAs is characterized because the medical literature investigating this is controversial and using suitable alternatives, patients usually can be accommodated. Expand
Nickel Allergy: Localized, Id, and Systemic Manifestations in Children
TLDR
Four children are presented to illustrate the different presentations of nickel allergy confirmed by patch testing and localized, id, and systemic nickel reactions are reviewed, as well as the diagnosis and management of nickel allergic contact dermatitis. Expand
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