Nickel Allergy and Our Children's Health: A Review of Indexed Cases and a View of Future Prevention

@article{Jacob2015NickelAA,
  title={Nickel Allergy and Our Children's Health: A Review of Indexed Cases and a View of Future Prevention},
  author={Sharon E Jacob and Alina Goldenberg and Janice L. Pelletier and L Fonacier and Richard P. Usatine and Nanette B Silverberg},
  journal={Pediatric Dermatology},
  year={2015},
  volume={32}
}
Nickel is the leading cause of allergic contact dermatitis (ACD) from early childhood through adolescence. Studies have shown that skin piercings and other nickel‐laden exposures can trigger the onset of nickel ACD in those who are susceptible. Nickel ACD causes a vast amount of cutaneous disease in children. Cases of nickel ACD in children have been reported in peer‐reviewed literature from 28 states. Common items that contain inciting nickel include jewelry, coins, zippers, belts, tools, toys… Expand
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Citation Type

Nickel Allergic Contact Dermatitis: Identification, Treatment, and Prevention
TLDR
Data point to nickel exposure as a trigger for elicitation of Ni-ACD and provide evidence that legislation can have a favorable effect on the economic and medical health of a population. Expand
Identification of Unreported Sources of Objects Containing High Release Nickel
Globally, nickel is the leading cause of allergic contact dermatitis (ACD). Nickel is ubiquitous, and published literature continues to index items most frequently associated with NiACD. Unregulated… Expand
Hidden risks in toys: A systematic review of pediatric toy contact dermatitis
TLDR
There is still an unmet need for observation of this segment of industry for labeling of contents and ongoing surveillance of contact dermatitis in children's toys. Expand
Epidemiology of nickel sensitivity: Retrospective cross‐sectional analysis of North American Contact Dermatitis Group data 1994‐2014
TLDR
The frequency of nickel sensitivity in patients referred for patch testing has significantly increased over a 20‐year period and is of substantial public health importance in North America. Expand
Pediatric Allergic Contact Dermatitis. Part I. Clinical Features and Common Contact Allergens in Children.
TLDR
Diagnosis can be difficult in children, as the appearance of ACD can mimic other common pediatric skin conditions, particularly atopic dermatitis and irritant contact dermatitis, as ACD tends to persist if the allergen is not identified and can affect patients' quality of life. Expand
Belt Buckles—Increasing Awareness of Nickel Exposure in Children: A Case Report
TLDR
Allergic contact dermatitis in 12 children with peri-umbilical nickel dermatitis (with and without generalized involvement) caused by dimethylglyoxime-positive belt buckles is described. Expand
Pediatric Allergic Contact Dermatitis: Clinical and Epidemiological Study in a Tertiary Hospital ☆
TLDR
More than half of the children studied showed sensitization to 1 or more allergens, with a high percentage of relevant sensitizations, and all children with a clinical suspicion of allergic contact dermatitis should be referred for patch testing. Expand
The “Jewelry Addict”: Allergic Contact Dermatitis from Repetitive Multiple Children's Jewelry Exposures
TLDR
The case illustrates the importance of investigating a range of different types of allergens when evaluating for jewelry sensitivity in children with frequent use of accessories, including rubber jewelry, plastics, dyed yarns, beads, metals, and ceramics. Expand
Pediatric patch testing: A 10-year retrospective study.
TLDR
The study of pediatric patch testing can provide information regarding common allergens in children, which can enhance patient care and primary care practitioners may benefit from awareness of patch testing as an alternative to prescribing systemic immunosuppressants. Expand
Contact Allergens in Food Handlers of Kashmir Valley in North India.
TLDR
With the high rates of nickel sensitization, a US-based nickel release directive targeting items intended to come into direct and prolonged skin contact is needed. Expand
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