Ngoye virus: a novel evolutionary lineage within the genus Flavivirus.

@article{Grard2006NgoyeVA,
  title={Ngoye virus: a novel evolutionary lineage within the genus Flavivirus.},
  author={Gilda Grard and J J Lemasson and Massamba Sylla and Audrey Dubot and Shelley Cook and J. F. Molez and Xavier Pourrut and Remi N. Charrel and Jean Paul Gonzalez and Ulrike G Munderloh and Edward C. Holmes and Xavier de Lamballerie},
  journal={The Journal of general virology},
  year={2006},
  volume={87 Pt 11},
  pages={
          3273-7
        }
}
By using degenerate primers deduced from conserved patterns in the flavivirus polymerase gene, a novel RNA virus was discovered in Rhipicephalus ticks sampled from members of the family Bovidae in Senegal. It was named Ngoye virus (NGOV) after the location from which it was isolated. Viral particles could be observed by electron microscopy, but isolation in vertebrate or invertebrate cell lines or by intracerebral infection of newborn mice remained unsuccessful. This is atypical of recognized… Expand
A New Flavivirus and a New Vector: Characterization of a Novel Flavivirus Isolated from Uranotaenia Mosquitoes from a Tropical Rain Forest
TLDR
Phylogenetic analyses of the whole polyprotein and the NS3 protein showed that the virus forms a distinct cluster within the clade of mosquito-borne flaviviruses, indicating that NOUV is a novel lineage within the Flaviviridae. Expand
Characterization of a Novel Flavivirus from Mosquitoes in Northern Europe That Is Related to Mosquito-Borne Flaviviruses of the Tropics
TLDR
Phylogenetic analysis of the complete coding sequence showed that LAMV represented a distinct lineage related to the Aedes sp.-transmitted human pathogenic flaviviruses, similarly to the newly described Nounané virus, a flavivirus from Africa. Expand
Divergent Viruses Discovered in Arthropods and Vertebrates Revise the Evolutionary History of the Flaviviridae and Related Viruses
TLDR
The traditional view on the evolutionary history, host range, and genomic structures of a major group of RNA viruses is revised, suggesting that arthropods may be the ultimate reservoir of the Flaviviridae and related viruses, harboring considerable genetic and phenotypic diversity. Expand
New Insights into Flavivirus Evolution, Taxonomy and Biogeographic History, Extended by Analysis of Canonical and Alternative Coding Sequences
TLDR
A timescale for a relevant subset of flaviviruses whose evolutionary history, shows that different Culex-spp. Expand
Evolution of the sequence composition of Flaviviruses.
  • Alyxandria M. Schubert, C. Putonti
  • Biology, Medicine
  • Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
  • 2010
TLDR
Examination of the species within this particular genus that infect vertebrate hosts revealed that sequence composition proclivities do not correspond with vector transmission as the evolutionary history of this species suggests. Expand
An African tick flavivirus forming an independent clade exhibits unique exoribonuclease-resistant RNA structures in the genomic 3′-untranslated region
TLDR
It is reported that a novel flavivirus, Mpulungu flaviv virus (MPFV), was discovered in a Rhipicephalus muhsamae tick in Zambia, and it is clarified that two xrRNA structures of MPFV in the 3′-UTR could prevent exoribonuclease activity. Expand
Novel flaviviruses from mosquitoes: Mosquito-specific evolutionary lineages within the phylogenetic group of mosquito-borne flaviviruses
TLDR
An overview of MBFV-related viruses concludes that they differ from the ISFs genetically and antigenically, and provide new information on the variety, properties and evolution of vector-borne flaviviruses. Expand
Characterization of an insect-specific flavivirus (OCFVPT) co-isolated from Ochlerotatus caspius collected in southern Portugal along with a putative new Negev-like virus
TLDR
The isolation and characterization of an insect-specific flavivirus (ISF) from Ochlerotatuscaspius mosquitoes collected in southern Portugal is described and the cytopathic effects associated with its presence in culture supernatants are postulated to be the result of the replication of a co-isolated putative new Negev-like virus. Expand
The Discovery of Arthropod-Specific Viruses in Hematophagous Arthropods: An Open Door to Understanding the Mechanisms of Arbovirus and Arthropod Evolution?
TLDR
This review focuses specifically on arthropod viruses in hematophagous arthropods, a recently recognized and obviously important virus group that has genomes analogous to viruses in various families that include arboviruses and nonarbovirus. Expand
Structure and functionality in flavivirus NS-proteins: Perspectives for drug design
TLDR
Structural and functional aspects emerging from the characterization of two main components (NS3 and NS5 proteins) of the flavivirus replication complex are reviewed to shed light on the design and development of antiviral drug leads. Expand
...
1
2
3
...

References

SHOWING 1-10 OF 22 REFERENCES
Genome sequence analysis of Tamana bat virus and its relationship with the genus Flavivirus.
TLDR
Analysis based on both genetic distances and maximum-likelihood confirmed that TABV is more closely related to the flaviviruses than to the other genera, which has implications for the evolutionary history and taxonomic classification of the family as a whole. Expand
Isolation of a new strain of the flavivirus cell fusing agent virus in a natural mosquito population from Puerto Rico.
TLDR
Results from viral screening, and cell culture and molecular identification of the infected mosquitoes are presented, supporting previous suggestions of the existence of a large number of unsampled flaviviruses and elucidating the mechanism by which flaviviral sequences may have integrated into mosquito genomes. Expand
Phylogeny of the genus flavivirus using complete coding sequences of arthropod-borne viruses and viruses with no known vector
TLDR
Comparative genetic amino acid alignments revealed that p-distance cut-off values of 0·330–0·470 distinguished the arthropod-borne viruses according to their recognized serogroups and Rio Bravo and Apoi virus were assigned to two distinct non-vectored virus groups. Expand
Identification of new flaviviruses in the Kokobera virus complex.
TLDR
It is proposed that isolate TS5273 represents a new subtype of KOKV and that CY1014 be classified as a novel species within the Kokobera virus complex of flaviviruses, named New Mapoon virus. Expand
Phylogeny of the Genus Flavivirus
TLDR
The phylogenetic study revealed for the first time that from the putative ancestor two branches, non-vector and vector-borne virus clusters, evolved and from the latter cluster emerged tick-borne and mosquito-borne viruses clusters. Expand
Genetic and phenotypic characterization of the newly described insect flavivirus, Kamiti River virus
TLDR
The isolation of KRV demonstrates the presence of an insect-only flavivirus in nature and raises questions regarding potential interactions between this virus and other mosquito-borne viruses in competent vector populations. Expand
Phylogenetic relationships of flaviviruses correlate with their epidemiology, disease association and biogeography.
TLDR
Phylogenetic analysis of the Flavivirus genus revealed an extensive series of clades defined by their epidemiology and disease associations, which revealed distinct geographical clusters in either the Old World or the New World, which for mosquito-borne viruses may reflect an Old World origin. Expand
A multigene analysis of the phylogenetic relationships among the flaviviruses (Family: Flaviviridae) and the evolution of vector transmission
TLDR
This most comprehensive phylogenetic study to date, involving maximum likelihood analyses of the NS3 and NS5 genes and the entire genome sequences available at present, shows that (i) the NS5 gene contains insufficient phylogenetic signal to choose between competing topological hypotheses, and (ii) the whole genome data indicate that the mosquito-borne flaviviruses represent an outgroup to the remaining flavivirus. Expand
Taxonomy of the virus family Flaviviridae.
TLDR
Current taxonomic placement of Flaviviruses comprises one of three genera within the virus family Flavoriviridae, which contains a single long open reading frame flanked by 50- and 30-terminal noncoding regions that form specific secondary stem–loop structures required for genome replication. Expand
Sequences of flavivirus-related RNA viruses persist in DNA form integrated in the genome of Aedes spp. mosquitoes.
TLDR
These flavivirus-related integrated DNA sequences were detected in laboratory-bred and wild Aedes albopictus and Aedes aegypti mosquitoes, demonstrating that their discovery is not an artefact resulting from the manipulation of mosquito cell lines, since they exist under natural conditions. Expand
...
1
2
3
...