Next-generation sequencing reveals cryptic mtDNA diversity of Plasmodium relictum in the Hawaiian Islands.

@article{Jarvi2013NextgenerationSR,
  title={Next-generation sequencing reveals cryptic mtDNA diversity of Plasmodium relictum in the Hawaiian Islands.},
  author={Susan I Jarvi and Margaret E.m. Farias and Dennis A Lapointe and Mahdi Belcaid and Carter T. Atkinson},
  journal={Parasitology},
  year={2013},
  volume={140 14},
  pages={
          1741-50
        }
}
Next-generation 454 sequencing techniques were used to re-examine diversity of mitochondrial cytochrome b lineages of avian malaria (Plasmodium relictum) in Hawaii. We document a minimum of 23 variant lineages of the parasite based on single nucleotide transitional changes, in addition to the previously reported single lineage (GRW4). A new, publicly available portal (Integroomer) was developed for initial parsing of 454 datasets. Mean variant prevalence and frequency was higher in low… CONTINUE READING
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