Next-generation sequencing in the analysis of human microbiota: essential considerations for clinical application.

@article{Rogers2010NextgenerationSI,
  title={Next-generation sequencing in the analysis of human microbiota: essential considerations for clinical application.},
  author={Geraint Berian Rogers and Kenneth Deans Bruce},
  journal={Molecular diagnosis & therapy},
  year={2010},
  volume={14 6},
  pages={343-50}
}
The development of next-generation sequencing (NGS) presents an unprecedented opportunity to investigate the complex microbial communities that are associated with the human body. It offers for the first time a basis for detailed temporal and spatial analysis, with the potential to revolutionize our understanding of many clinically important systems. However, while advances continue to be made in areas such as PCR amplification for NGS, sequencing protocols, and data analysis, in many cases the… CONTINUE READING

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