Next-generation anthracycline for the management of small cell lung cancer: focus on amrubicin

  title={Next-generation anthracycline for the management of small cell lung cancer: focus on amrubicin},
  author={Michiko Yamamoto and Akira Takakura and N. Masuda},
  booktitle={Drug design, development and therapy},
Amrubicin is a totally synthetic anthracycline anticancer agent that acts as a potent topoisomerase II inhibitor. Amrubicin has been approved in Japan for the treatment of lung cancer, and the results from clinical studies of amrubicin as a single agent or as part of combination regimens for lung cancer, particularly for small cell lung cancer, conducted in Japan and overseas have been promising. Amrubicin should be included among new treatment strategies especially for chemoresistant patients… CONTINUE READING

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