Newly synthesized protein secretion in rat lacrimal gland: post-second messenger synergism.

@article{Mauduit1987NewlySP,
  title={Newly synthesized protein secretion in rat lacrimal gland: post-second messenger synergism.},
  author={Philippe Mauduit and G Dolder Herman and Bernard Rossignol},
  journal={The American journal of physiology},
  year={1987},
  volume={253 4 Pt 1},
  pages={
          C514-24
        }
}
The vasoactive intestinal peptide (VIP) induces a concentration-dependent secretion of newly synthesized (3H labeled) proteins from lacrimal gland fragments. Maximal secretory response is approximately 20% of total labeled proteins secreted for a 40-min stimulation and half-maximal secretory response is obtained at 3.8 +/- 0.2 nM VIP. The cholinergic (muscarinic) and VIPergic stimulations synergistically interact in eliciting newly synthesized protein secretion. Carbachol (0.3 microM) and the… CONTINUE READING
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