Newly divided eosinophils limit ozone-induced airway hyperreactivity in nonsensitized guinea pigs.

@article{Wicher2017NewlyDE,
  title={Newly divided eosinophils limit ozone-induced airway hyperreactivity in nonsensitized guinea pigs.},
  author={Sarah A Wicher and David B Jacoby and Allison D Fryer},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2017},
  volume={312 6},
  pages={L969-L982}
}
Ozone causes vagally mediated airway hyperreactivity and recruits inflammatory cells, including eosinophils, to lungs, where they mediate ozone-induced hyperreactivity 1 day after exposure but are paradoxically protective 3 days later. We aimed to test the role of newly divided eosinophils in ozone-induced airway hyperreactivity in sensitized and… CONTINUE READING