Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2


Genome-wide association studies (GWAS) have identified seven breast cancer susceptibility loci, but these explain only a small fraction of the familial risk of the disease. Five of these loci were identified through a two-stage GWAS involving 390 familial cases and 364 controls in the first stage, and 3,990 cases and 3,916 controls in the second stage. To… (More)
DOI: 10.1038/ng.354


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@article{Ahmed2009NewlyDB, title={Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2}, author={S. Ahmed and G. Neil Thomas and Maya Ghoussaini and Catherine S. Healey and Manjeet K. Humphreys and Radka Platte and Jonathan Morrison and Melanie J Maranian and Karen A. Pooley and Robert N Luben and Diana Eccles and D. Gareth Evans and Olivia Fletcher and Nichola Johnson and I. Silva and Julian Peto and Michael R. Stratton and Nazneen Rahman and Kevin T. Jacobs and Ross L. Prentice and Garnet L. Anderson and Aleksandar Rajkovic and Jess David Curb and Regina G. Ziegler and C Berg and Saundra S. Buys and Catherine A. McCarty and Heather Spencer Feigelson and Eugenia E. Calle and Michael J. Thun and William Ryan Diver and S E Bojesen and B\orge G. Nordestgaard and Henrik Flyger and Thilo D{\"o}rk and Peter Schuermann and Peter Hillemanns and Johann Hinrich Karstens and Natalia Valerijevna Bogdanova and Natalia N. Antonenkova and Iosif Viktorovich Zalutsky and Marina A Bermisheva and Sardana Fedorova and Elza Khusnutdinova and D. Kang and Keun-young Yoo and Dong - Young Noh and Sei Hyun Ahn and Peter Devilee and Christi J. van Asperen and R. A. E. M. Tollenaar and Caroline M. Seynaeve and Montserrat Garc{\'i}a-Closas and Jolanta Lissowska and Louise Brinton and Beata Pepłońska and Heli Nevanlinna and Tuomas Heikkinen and Kristiina Aittom{\"a}ki and Carl Blomqvist and John L. Hopper and Melissa C. Southey and Letitia Smith and Amanda B. Spurdle and Marjanka K. Schmidt and Annegien Broeks and Richard R van Hien and S A P Cornelissen and Roger L Milne and Gloria Ribas and Anna Gonz{\'a}lez-Neira and Javier Ben{\'i}tez and Rita Schmutzler and Barbara Burwinkel and Claus Rainer Bartram and Alfons Meindl and Hiltrud Brauch and Christina Justenhoven and Ute Hamann and Jenny Chang-Claude and Rebecca Hein and Shan Wang-gohrke and A. Arto Lindblom and Sara J. Margolin and Arto J Mannermaa and V. M. Kosma and Vesa V. Kataja and Janet E. Olson and Xianshu Wang and Zachary S. Fredericksen and Graham G. Giles and Gianluca Severi and Laura Baglietto and Dallas R. English and Susan E. Hankinson and David G. Cox and Peter Kraft and Lars J Vatten and Kristian Hveem and Merethe H Kumle and Alice J. Sigurdson and Michele Morin Doody and Parveen Bhatti and Bruce H. Alexander and Maartje Joanneke Hooning and Ans M. W. van den Ouweland and Rogier A. Oldenburg and Mieke Schutte and Per Hall and Kamila Czene and Jianjun Liu and Yuqing Li and Angela Cox and Graeme C. Elliott and Ian Wallace Brock and Malcolm Reed and Chen-yang Shen and Jyh-cherng Yu and Giu-Cheng Hsu and Shou-Tung Chen and Hoda Anton-Culver and Argyrios Ziogas and Irene L. Andrulis and J. A. G. Knight and Jonathan Beesley and Ellen L. Goode and Fergus J. Couch and Georgia Chenevix-Trench and Robert N. Hoover and Bruce A. J. Ponder and David J. Hunter and Paul D. P. Pharoah and Alison M. Dunning and Stephen J. Chanock and Douglas F. Easton}, journal={Nature Genetics}, year={2009}, volume={41}, pages={585-590} }