Newly discovered angiogenesis inhibitors and their mechanisms of action

@inproceedings{Miao2012NewlyDA,
  title={Newly discovered angiogenesis inhibitors and their mechanisms of action},
  author={Ze-Hong Miao and Jian-ming Feng and Jian Ding},
  booktitle={Acta Pharmacologica Sinica},
  year={2012}
}
In the past decade, the success of angiogenesis inhibitors in clinical contexts has established the antiangiogenic strategy as an important part of cancer therapy. During that time period, we have discovered and reported 17 compounds that exert potent inhibition on angiogenesis. These compounds exhibit tremendous diversity in their sources, structures, targets and mechanisms. These studies have generated new models for further modification and optimization of inhibitory compounds, new… CONTINUE READING

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